Lipoic Acid Supreme is a mixture of high dose lipoic acid, biotin, and taurine, which all support blood sugar and insulin balance. Lipoic acid increases the need for biotin by lowering levels of biotin dependent enzymes. Thus Lipoic Acid should always be taken with biotin. Lipoic Acid Supreme contains high dose lipoic acid, biotin, and taurine which all support blood sugar and insulin balance, making a great combination. Lipoic Acid has been extensively researched for its applications in diabetes, blood sugar metabolism, heavy metal detoxification, liver health, hepatitis, and diabetic neuropathy. Lipoic acid has also been studied for its effects on the aging process and in the prevention of wrinkling by protecting collagen in the skin. Most importantly, it has been found to be an essential nutrient for diabetics to optimize the function of the insulin receptors.